Fullerene itaconic acid copolymer lead salt was prepared via two steps reaction using C60　, itaconic acid and lead nitrate as raw materials. The structure of the product was characterized by FT-IR, UV-Vis, XPS and AAS. Under air atmosphere, the thermal stability of the target product was analyzed by DTA and TG. Results show that the suitable technological conditions to prepare fullerene itaconic acid copolymer lead salt are determined as: reaction temperature of 25℃ and pH value of 6.9. The decomposition peak temperature of the product is 304℃, which shows good thermal stability.